C-Phycocyanin – Spirulina Extract

Cancer Prevention
• It exhibited antiproliferative activity against human cancer cells through apoptosis; nuclear apoptosis induction was accompanied by G0/G1 phase arrest and DNA fragmentation. It is a natural pigment with potential as an anticancer agent.
  https://pubmed.ncbi.nlm.nih.gov/23578642/
• Phycocyanin exerts anti-cancer activity by blocking tumor cell cell cycle, inducing tumor cell apoptosis and autophagy, thereby phycocyanin can serve as a promising anti-cancer agent.
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687155/
Anti-Fungal
• phycocyanin inhibited the growth of all the five fungal species tested even at low concentrations.
  https://www.researchgate.net/publication/301540976_Screening_for_Antifungal_and_Antiviral_activity_of_C-phycocyanin_from_Spirulina_platensis
Anti-Viral
• It exerted antiviral activities in Vero cells by interfering with viral adsorption. The inhibition of HSV-1 was 61% and HSV-2 was 81.7% when treated with algal filtrate at the concentration of 390.6µg/ml.
  https://www.researchgate.net/publication/301540976_Screening_for_Antifungal_and_Antiviral_activity_of_C-phycocyanin_from_Spirulina_platensis
Protects Liver
• The efficacy of C-phycocyanin obtained from Arthrospira maxima SAG 25780 was evaluated on the levels of lipid peroxidation, and antioxidant parameters as well as histopathological and immunohistochemical assessment in carbon tetrachloride(CCl4) induced liver damage in the male Wistar albino rats.
  https://www.sciencedirect.com/science/article/abs/pii/S2210523911000766
Anti-oxidant
• It has beneficial effects on the development of porcine parthenotes by attenuating mitochondrial dysfunction and oxidative stress.
  https://pubmed.ncbi.nlm.nih.gov/29208995/
Anti-inflammatory
• It reduced edema, histamine (Hi) release, myeloperoxidase (MPO) activity and the levels of prostaglandin (PGE2) and leukotriene (LTB4) in the inflamed tissues.
  https://www.eurekaselect.com/81056/article
Protects Brain Health
• It reduced the levels of tumor necrosis factor (TNF-α) in the blood serum of mice treated with endotoxin and it showed neuroprotective effects in rat cerebellar granule cell cultures and in kainate-induced brain injury in rats.
  https://www.eurekaselect.com/81056/article
• C-PC treatment resulted in a) decrease in the levels of tryptophan and markers of lipid peroxidation and b) elevation in the activity levels of catalase, glutathione peroxidase in different regions of brain.
  https://pubmed.ncbi.nlm.nih.gov/17169376/

Chlorella

Immune Booster
• Salivary secretory immunoglobulin A secretion increases after 4-weeks ingestion of chlorella-derived multicomponent supplement in humans.
  https://pubmed.ncbi.nlm.nih.gov/21906314/
• Beneficial immunostimulatory effect of short-term Chlorella supplementation enhances the NK cell activity and produces interferon-γ and interleukin-12 as well as interleukin-1β, the Th-1 cell-induced cytokines in healthy people.
  https://pubmed.ncbi.nlm.nih.gov/22849818/

Anti-Oxidant
• The beneficial aspects of Chlorella on atherosclerosis could be ascribed, at least in part, to its AGE inhibitory property and that Chlorella may have therapeutic potentials in treatment of patients with other AGE-related disorders such as diabetic microangiopathy and Alzheimer’s disease.
  https://pubmed.ncbi.nlm.nih.gov/15996828/
• Chlorella vulgaris exhibited bioprotective effects especially in cells obtained from young donor but were more bioremediative for cells obtained from old donor as indicated by DNA damage, telomere shortening and reduction in telomerase activity.
  https://pubmed.ncbi.nlm.nih.gov/20606778/
• Supplementation with C. vulgaris extract significantly improves antioxidant status and attenuates lipid peroxidation in chronic cigarette smokers. Hence, C. vulgaris might prevent the disease burden and mortality rate associated with smoking.
  https://pubmed.ncbi.nlm.nih.gov/23865357/

All 9 essential Amino Acids
• It contains all nine essential amino acids and acylcarnitine.
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896938/

>50% Protein
• Chlorella is about 50-60% protein.
  https://www.sciencedirect.com/science/article/abs/pii/S1364032114002342

Body Detox – Binding with heavy metal
• Chlorella supplementation not only reduces dioxin levels in breast milk and may also have beneficial effects on nursing infants by increasing IgA levels in breast milk. Dioxins are environmental pollutants.
  https://pubmed.ncbi.nlm.nih.gov/17472477/

Aloe Vera

Anti-Bacterial
• Specific plant compounds such as anthraquinones and dihhydroxyanthraquinones as well as saponins have been proposed to have direct antimicrobial activity.
  https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.415.3003&rep=rep1&type=pdf
• Aloe vera mouthrinse is equally effective in reducing plaque as Chlorhexidine compared to placebo over a period of 4 days.
  https://pubmed.ncbi.nlm.nih.gov/24795515/

Anti-Fungal
• Aloe vera extracts have been shown to inhibit the growth of fungi that cause tinea.
  https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.415.3003&rep=rep1&type=pdf

Wound Healing
• Aloe vera has been used to prevent skin ulcers and to treat burn wounds, postoperative wounds, cracked nipples, genital herpes, psoriasis, and chronic wounds including pressure ulcers.
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330525/

Lowers Blood Sugar
• Eight trials involving 470 patients showed Aloe vera may improve glycaemic control in type 2 diabetes, with a marginal improvement in FPG and a significant improvement in HbA1c.
  https://pubmed.ncbi.nlm.nih.gov/27009750/

Natural Laxative
• Aloe contains pharmacologically active ingredients associated with diverse biological activities including fungicidal, antiviral, antibacterial, anti-inflammatory, antimicrobial, laxative, immunomodulating, and anticancer effects.
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349368/

Anti-Oxidant
• Aloe vera gel had strong immunomodulatory activity, downregulating lipopolysaccharide-induced inflammatory cytokine production and NLRP3 inflammasome expression in human macrophages. Acemannan stimulated immunity through potentiating the lymphocyte response to alloantigen with nitric oxide production activation by macrophages and cytokines, such as interleukin (IL)-1, IL-6, interferon (IFN), and TNF-α. It enhanced phagocytosis and also increased circulating monocyte and macrophage levels. Polysaccharide aloeride activated nuclear factor (NF)-ĸB in human macrophages similar to bacterial endotoxin.
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163315/

Wheat Grass

Boosts Immunity
• wheatgrass-derived oligosaccharides (WG-PS3) were isolated and found to induce CD69 and Th1 cytokine expression in human peripheral blood mononuclear cells. They directly activated the purified monocytes by inducing the expression of CD69, CD80, CD86, IL-12, and TNF-α Maltoheptaose activated monocytes via Toll-like receptor 2 (TLR-2) signaling, as discovered by pretreatment of blocking antibodies against Toll-like receptors (TLRs).
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682569/

Prevent Obesity, Boost Metabolism
• Dietary supplementation with thylakoids thus affects satiety both via appetite hormones and GI fullness, and affects the microbial composition without causing GI adverse effects such as steatorrhea. This suggests thylakoids as a novel agent in prevention and treatment of obesity.
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059972/
• 6 weeks significantly decreased the body weights, serum total cholesterol (TC), and low-density lipoprotein cholesterol levels in HFD-fed mice. TAEE treatment reduced lipid accumulation in epididymal white adipose tissue (EWAT) and liver. Moreover, TC and lipid levels were decreased by TAEE treatment in liver. Serum leptin and adiponectin concentrations were reduced by TAEE treatment.
  https://www.tandfonline.com/doi/full/10.1080/09168451.2015.1006567

Improves Heart Health
• Study revealed hypolipidemic effect of Wheat Grass in hypercholesterolemic rats by increasing fecal cholesterol excretion. Fresh GJ could have potentially beneficial effect in atherosclerosis associated with hyperlipidemia.
  https://pubmed.ncbi.nlm.nih.gov/21485304/
• Wheat grass supplementation with a high-fat diet resulted in improved lipid levels (decreased total cholesterol and increased HDL-C) together with significantly reduced MDA levels and increased GSH and vitamin C levels. These results indicate the beneficial role of wheat grass in ameliorating hyperlipidemia and the associated oxidative stress.
  https://pubmed.ncbi.nlm.nih.gov/20508870/

Protects against several diseases
• The wheatgrass ointments helps to decrease various skin problems like eczema, itchy skins, etc.
  • Latest Researches found that insertion of wheatgrass chlorophyll packs into the sinuses clears the congestion. It also helps to cure chronic sinusitis
  • Chlorophyll also has beneficial effects on heart, vascular system, intestine, uterus and lungs.
  • Wheatgrass juice has superior detoxifying agent.
  • The small amount of wheatgrass in diet regularly prevents tooth decay and reduces tooth aches also.
  • Wheatgrass juice helps to prevent diabetes, hypertension, graying of hair, pyorrhea of mouth, arthritis.
  • It improves digestion and can be used as effective skin cleanser. Wheatgrass juice removes heavy metals and is useful to treat various blood disorders.
    https://www.rroij.com/open-access/a-mini-review-on-wheatgrass-.pdf
  • Wheatgrass is known to help minimize fatigue, improve sleep, increase strength, naturally regulate blood pressure and blood sugar, support weight loss, improve digestion and elimination, support healthy skin, teeth, eyes, muscles and joints, improve the function of our heart-lungs and reproductive organs, heal ulcers and skin sores, slow cellular aging, improve mental function, and is beneficial in arthritis and muscle cramping.
  • It is proven to be beneficial under various conditions, such as anaemia, diabetes, cancer, eczema, constipation, kidney swelling, and common cold.
    https://www.functionalfoodscenter.net/files/47516971.pdf

Anti-oxidant
• Wheat grass contains many anti-oxidants, phenolic and flavonoid anti-oxidants. These extracts were also found to inhibit significantly ascorbate-Fe2+ induced lipid peroxidation in rat liver mitochondria.
  https://pubmed.ncbi.nlm.nih.gov/16521113/

Anti-Inflammatory
• Chlorophyll a and its degradation products are valuable and abundantly available anti-inflammatory agents and promising for the development of phytomedicine or conventional medicine to treat inflammation and related diseases.
  https://pubmed.ncbi.nlm.nih.gov/22038065/
• CRCs exert anti-inflammatory effects through modulation of NF-κB and AP-1 signaling.
  https://pubmed.ncbi.nlm.nih.gov/24066944/

Anti-Bacterial
• Wheat grass extract demonstrated anti-microbial activity against S. mutans and Lactobacillus spp.
  https://www.jdrr.org/article.asp?issn=2348-2915;year=2015;volume=2;issue=2;spage=70;epage=72;aulast=Rajpurohit

Moringa

Anti-Fungal
• The chloroform extract of Moringa oleifera flowers showed the better antifungal activity, inhibiting the growth of all tested fungal strains.
  https://www.scielo.br/scielo.php?script=sci_arttext_pr&pid=S0103-84782014010900001&tlng=en
• Moringa has alkaloids flavonoids, glycosides, tannins, triterpenoids and steroids that attribute to its anti-fungal properties. the plant extracts showed antifungal activity against Rizopus stolonifer and Microsporum gypsum.
  https://www.imedpub.com/articles/antifungal-efficacy-of-moringa-oleifera-lam.pdf

Anti-Viral
• Moring showed significant activities against viruses like HIV, HSV, HBV, EBV, FMDV and NDV.
  https://www.sciencedirect.com/science/article/abs/pii/S0254629919305150
• Moringa A has potent antiviral activity against IVAs, which could be due to the autophagy inhibition property.
  https://assets.researchsquare.com/files/rs-135760/v1/8899cf64-7776-4e29-b009-1476a16d9f94.pdf

Anti-Depressant
• The antidepressant effect of MOE may have been invoked through the noradrenergic-serotonergic neurotransmission pathway, which is the hallmark of selective serotonin reuptake inhibitors (SSRI) class of drugs.
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719488/

Improves Hair Health
• The iron in moringa brings oxygen to the roots. The zinc in moringa stimulates hair growth. The essential amino acids in moringa build healthy hair strands. Vitamins c & e in moringa fight oxidative stress. The omega 3s in moringa nourish hair.
  https://blog.kulikulifoods.com/2020/05/08/moringa-benefits-hair/

Improves Heart & Digestive Health
• Supplementation of DLP and ALP significantly increased serum retinol, serum ascorbic acid, glutathione peroxidase, superoxide dismutase, whereas decrease in marker of oxidative stress i.e. malondialdehyde. A significant decrease was also observed in fasting blood glucose level and increase in haemoglobin.
  https://link.springer.com/article/10.1007/s13197-012-0859-9
• Leaves of Moringa oleifera have definite hypocholesterolemic activity and that there is valid pharmacological basis for employing them for this purpose in India.
  https://pubmed.ncbi.nlm.nih.gov/10661880/
• Moringa oleifera was found to increase the excretion of faecal cholesterol.
  https://pubmed.ncbi.nlm.nih.gov/12738086/

Anti-Inflammatory
• M. oleifera leaves possess peripherally non-opioid mediated and centrally opioid mediated antinociceptive and anti-inflammatory activities. This study also confirms the traditional uses of M. oleifera in the treatment of ailments, particularly those related to pain and inflammation.
  https://www.tandfonline.com/doi/full/10.1080/13880200802366710
• Moringa inhibits spleen weight as well as circulatory leukocyte and splenocyte counts. The production of the humoral antibody titer was significantly ameliorated at a dose of 100 and 200mg/kg . Furthermore, the extract caused a down-regulation of macrophage phagocytosis due to carbon particles.
  https://pubmed.ncbi.nlm.nih.gov/20435128/